I'm not sure if this is a good fit on this forum, but I guess graphics is an integral part of bioinformatics, so here goes. I wish to create a heatmap like the one in panel D in this figure. I could plot the heatmap easily, but I couldn't find how to put the contour lines and numbers on it. Is there a package/command in R/Python or maybe they wrote a custom script. Any help is much appreciated. Thanks!