How to create protein protein interaction network from HPRD database
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6.5 years ago

I have a list of differentially expressed genes of two diseases and want to create diseasome network like this http://journals.plos.org/plosone/article/figure?id=10.1371/journal.pone.0149175.g002. Please, can anyone help? I have queried for protein interactions in HPRD site. am I doing right? for every gene, i am doing like same. As I am new for this, I have a doubt whether I am doing correct or not. after identifying the proteins, they have made graph Psoriasis diseaseome along with proteins common in AD and so on. have they taken only genes or genes and their interaction proteins also? which tools they have used for creating the figure.

are there are any online resources to learn diseasome construction, please send links.

genome next-gen RNA-Seq gene ChIP-Seq • 2.0k views
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