protein-protein orientation in fusion

Question

[12021560-002]

Hi, I am interesting in fusion of three or more antigens in a such a manner that their epitopes remain exposed. Is there any tool which may help to predict that what should be the orientation of these proteins. Your help will be greatly appreciated.

[natasha.sernova]

There were several such papers:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635942/pdf/khvi-11-09-1061159.pdf

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615220/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726540/

There are a lot of protein fusion posts in Biostars:

Where To Find A Database About Fusion Protein Ant Its Interaction Partner?

Protein Protein Or Protein Dna/Rna Interaction Prediction

Determine identify of protein domains in a fusion protein

Fusion with strand orientation

See the right panel of the page for the others.