Question: tool for simulating genomes based on observed mutations?
gravatar for ramiroricardo
20 months ago by
ramiroricardo0 wrote:

I have sequenced a set of bacterial clones, derived from the same reference strain, and identified a few thousand mutations. Sometimes I have more than one mutation in the same gene and I would like to know whether those cases are expected or not, given a random distribution of mutations.

I was thinking that I could do this by simulating genomes of my reference strain with mutations following the same mutation spectrum as the one I have in my vcf file. Does anyone know of a tool that can achieve this?

ADD COMMENTlink written 20 months ago by ramiroricardo0
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 826 users visited in the last hour