Question: Tools for quantitative comparison of differential tissue gene expression?
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gravatar for Ellen O
16 months ago by
Ellen O10
Stellenbosch University
Ellen O10 wrote:

I am attempting to assess the expression of a gene list in blood vs brain tissue (since we use blood as a proxy). I am struggling to find a tool/ database that has quantitative data (correlation, r^2 results) that's easily comparable between tissues. Does anyone know of something like this? I am trying to prioritise genes based on similar expression levels in brain and blood.

Thanks!

ADD COMMENTlink modified 16 months ago by Biostar ♦♦ 20 • written 16 months ago by Ellen O10

Hello, why would a simple correlation analysis not suffice? You can even derive P values from a correlation test in order to increase confidence in the correlation and, then rank them based on P value (lowest to highest).

ADD REPLYlink written 16 months ago by Kevin Blighe41k

It might help to look around for papers that use what you're describing and copying/emulating their methods.

ADD REPLYlink written 16 months ago by Hussain Ather910
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