Job:Bioinformatics Scientist at Gritstone Oncology (Cambridge, MA)
Entering edit mode
5.8 years ago
Michele Busby ★ 2.2k

Hi All,

We are looking for Bioinformatics Scientist to work on personalized oncology treatments at Gristone Oncology. Having started in NGS bioinformatics at the very beginning, it is amazing for me to see bioinformatics driving treatments that are put into patients. I really enjoy this work, and I think this is a great opportunity to be in industry in a true research position. We are an early stage biotech with generous investor backing. And we have really cool data now which I would be happy to tell you more about.

If you are interested, please send your resume and cover letter to We do not usually sponsor visas.

Here is the description:

Position Summary:

Gritstone Oncology is a privately-held, next-generation personalized cancer immunotherapy company. Gritstone brings together distinguished scientific founders, an experienced and diverse management team, a seasoned and successful board of directors and deep financial backing to tackle fundamental challenges at the intersection of cancer genomics, immunology, and immunotherapy design. The Company's initial goal is to identify and deploy neoantigens for novel treatments for lung and gastric cancer. In addition to neoantigen therapy development, Gritstone is leveraging its unique antigen discovery platform to define targets for shared antigen immunotherapies, which would provide an opportunity to treat even more patients.

Gritstone Oncology is headquartered in the San Francisco Bay Area with key functions located in Cambridge, MA and Pleasanton, CA. The company launched in October 2015 and has received funding from leading blue-chip biotechnology investors, including Versant Ventures, The Column Group, Clarus Funds, Frazier Healthcare Partners, RedMile, Casdin Capital, Lilly Asia Ventures, Trinitas Capital, GV, and Alexandria Venture Investments.

Gritstone Oncology is seeking a Bioinformatics Scientist to help harness the immune system to treat cancer. The Bioinformatics Scientist will perform analyses of industry leading proprietary and public genomic and proteomic datasets to find actionable biological insights.

We are looking for an independent and flexible team player who will thrive in a fast-paced, dynamic, and highly collaborative environment. This is an opportunity to work for a well-funded early biotechnology company where bioinformatics analyses drive personalized cancer treatments.

Specific responsibilities:

  • Develop and perform novel, rigorous bioinformatics analyses
  • Work closely with other computational and experimental scientists to design experiments
  • Effectively communicate findings to stakeholders

Minimum Education/Experience:

  • PhD in Bioinformatics or a related field or comparable work experience.
  • Training and experience in applying rigorous statistical methods for hypothesis testing to biological data
  • Track record of success in analyzing Mass Spectrometry or NGS data

Desired Experience:

  • Applying in-depth knowledge of cancer biology
  • Analysis of large, publicly-available datasets (e.g. GTEx, TCGA, ExAC)
  • Coding in python including Pandas
  • Software engineering including writing production-level code
  • Analysis of single cell data
  • Working in the cloud or on a high-performance computing cluster
RNA-Seq next-gen-sequencing • 1.5k views

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