I have a question regarding visualization of the large structural variations through IGV. I am visualizing large variations for a case. I observe dark red, blue and green reads which denotes deletion, insertion and duplication respectively according to the IGV manual. The reads have a insert size and have a mate region in other genes/regions. I want to ask if the insert size indicate size of deletion/insertion/duplication? I am observing insert size of 3.3 Mb, but the read is only 200-300 bp.