Question: Software to analyse mutational signatures other than DeconstructSigs R package
gravatar for peterodonovan
3.1 years ago by
peterodonovan0 wrote:

I am currently researching mutational signatures in Cancer genomes (see here for an explanation: ). I am using the DeconstructSigs package in R to analyze the data I have available. I was just wondering, do there exist other software for performing the same task that are seen as better? I know of the existence of the SomaticSignatures package but am unclear whether it is any better or worse than DeconstructSigs.

Any advice would be greatly appreciated!

cancer mutations R genome • 1.9k views
ADD COMMENTlink modified 3.1 years ago by poisonAlien3.0k • written 3.1 years ago by peterodonovan0
gravatar for poisonAlien
3.1 years ago by
poisonAlien3.0k wrote:

There are few other tools. DeconstructSigs estimates loading of known signatures for every sample in the cohort. If you are interested in de-novo you could try EMu and Mutational Signature framework. Both from Sanger.

ADD COMMENTlink written 3.1 years ago by poisonAlien3.0k
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1590 users visited in the last hour