Question: Machine Learning/Deep Learning approaches to integrate genotype and annotation information for predictions?
1
gravatar for Leandro Lima
3.0 years ago by
Leandro Lima960
San Francisco, CA
Leandro Lima960 wrote:

Hi, everyone.

I'm looking for some material (papers/tools) showing approaches to integrate genotype information (e.g. from WGS) and the variant/gene annotations to do predictions (e.g. age of onset, phenotype) with ML/DL.

Any recommendations?

Thanks in advance,
Leandro

ADD COMMENTlink modified 3.0 years ago by Hussain Ather940 • written 3.0 years ago by Leandro Lima960
0
gravatar for Hussain Ather
3.0 years ago by
Hussain Ather940
National Institutes of Health, Bethesda, MD
Hussain Ather940 wrote:

Guzzetta et al https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-11-S8-S3

ADD COMMENTlink written 3.0 years ago by Hussain Ather940

Thanks for the link, Hussain. They use genotype information, but they are not using any annotation (e.g. functional impact, frequency, etc.).

ADD REPLYlink written 3.0 years ago by Leandro Lima960
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