Question: Machine Learning/Deep Learning approaches to integrate genotype and annotation information for predictions?
1
gravatar for Leandro Lima
12 months ago by
Leandro Lima910
San Francisco, CA
Leandro Lima910 wrote:

Hi, everyone.

I'm looking for some material (papers/tools) showing approaches to integrate genotype information (e.g. from WGS) and the variant/gene annotations to do predictions (e.g. age of onset, phenotype) with ML/DL.

Any recommendations?

Thanks in advance,
Leandro

ADD COMMENTlink modified 12 months ago by Hussain Ather890 • written 12 months ago by Leandro Lima910
0
gravatar for Hussain Ather
12 months ago by
Hussain Ather890
National Institutes of Health, Bethesda, MD
Hussain Ather890 wrote:

Guzzetta et al https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-11-S8-S3

ADD COMMENTlink written 12 months ago by Hussain Ather890

Thanks for the link, Hussain. They use genotype information, but they are not using any annotation (e.g. functional impact, frequency, etc.).

ADD REPLYlink written 12 months ago by Leandro Lima910
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