Question: Machine Learning/Deep Learning approaches to integrate genotype and annotation information for predictions?
1
gravatar for Leandro Lima
3 months ago by
Leandro Lima880
San Francisco, CA
Leandro Lima880 wrote:

Hi, everyone.

I'm looking for some material (papers/tools) showing approaches to integrate genotype information (e.g. from WGS) and the variant/gene annotations to do predictions (e.g. age of onset, phenotype) with ML/DL.

Any recommendations?

Thanks in advance,
Leandro

ADD COMMENTlink modified 3 months ago by Hussain Ather820 • written 3 months ago by Leandro Lima880
0
gravatar for Hussain Ather
3 months ago by
Hussain Ather820
National Institutes of Health, Bethesda, MD
Hussain Ather820 wrote:

Guzzetta et al https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-11-S8-S3

ADD COMMENTlink written 3 months ago by Hussain Ather820

Thanks for the link, Hussain. They use genotype information, but they are not using any annotation (e.g. functional impact, frequency, etc.).

ADD REPLYlink written 3 months ago by Leandro Lima880
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 985 users visited in the last hour