Question: chipseq identified sequences
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gravatar for mkh
2.1 years ago by
mkh40
USA/CT
mkh40 wrote:

HI All,

I am not familiar with chip-seq data analysis. I would like to know why the chip-seq identified DNA sequences for one specific protein binding site has different lengths? for example the chipseq binding regions for protein A could be between 100-2000 bps? How the binding sites ranges determined from chip-seq data?

Thanks, Morteza

chip-seq • 626 views
ADD COMMENTlink modified 2.0 years ago by arup2.1k • written 2.1 years ago by mkh40
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gravatar for arup
2.0 years ago by
arup2.1k
India
arup2.1k wrote:

ChIP-seq data is mostly used for finding DNA binding motifs. The transcription factor binding motifs are generally short 8-12bp DNA sequences. Once motif has been identified the sequence is used as a quay for databases like JASPER, TRANSFACĀ® to find known transcription factor binding events.

ADD COMMENTlink written 2.0 years ago by arup2.1k
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