Entering edit mode
6.2 years ago
bipin
▴
30
The GSEA manual states that the signal2noise ranking metric should be used only in case of 3+ samples per condition.
What is the reason for this restriction?
I do understand that the denominator has standard deviations for the input values and it may be more meaningful in case of 3+ samples but how is it unsuitable in case of 2 samples?
Short and informative title, please.
Edit: Much better now, thanks.