Question: Rare variant meta-analyzing tests
gravatar for Floris Brenk
3 months ago by
Floris Brenk820
Floris Brenk820 wrote:

Hi all,

I have 5 different (dosage VCF files, with both continuous and binary phenotypes) datasets and I'm trying to meta-analyze rare variants in each dataset. Ideally I would like to group the variants per gene and then meta-analyze the p-values per gene from all 5 datasets, but I haven't found any software that easily does that. I played around a bit with rare metal and rvtests, but so far I keep on running into errors and weird results. Does anyone has any tips, ideas or tricks how to best do this? Any help is really appreciated!

ADD COMMENTlink modified 12 weeks ago • written 3 months ago by Floris Brenk820
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