I am having trouble resolving genomic positions from COSMIC, as some mutations simply do not seem to match the reference nucleotides. For example, I am looking at this mutation:
It says that G mutated to A, but on that position in hg38 the base is A. Reverse complementing doesn't solve the problem (I know that COSMIC has strand specific entries).
Also, looking at the COSMIC browser representation, we see that the mutation starts one position earlier:
All in all, I am thoroughly confused. The mutation is discovered in previous reference builds, so it persists, and there seems to be more of those. Anyone have an idea what is going on?
Thanks in advance!