Question: Where to download Normal exome bam for creating PoN (Panel of Normals) for cancer CNV workflow
gravatar for prabhakar8279
2.8 years ago by
prabhakar827910 wrote:


We are trying to get the copy number variation of the tumor only samples (from bam files) using the below workflow (not having paired normal samples)

and for preparing the PoN we plan to use the workflow in below link

Where do we download or get the normal samples (bam files) for creating the PoN (Panel of Normals)? If we have only one normal sample data (whole exome), can we use it instead of using more that one because the coverage is whole.

Can we use the normal exome data from this link


Can we use the exomes from the the 1000 genomes website for preparing the PoN.

Thanks Dr. Prabhakar

copy number variation • 2.6k views
ADD COMMENTlink modified 9 months ago by Karma300 • written 2.8 years ago by prabhakar827910

I suggest you to use data from or from

ADD REPLYlink modified 9 months ago by RamRS30k • written 9 months ago by Karma300

Karma while it is appreciate that you contribute, please be smart about your answers. You link the data portale from IternationalGenome, which 100% the link OP already posted. The EBI Dataset link is just a portal, this does not answer the question which data OP should use. Will move this to comment.

ADD REPLYlink written 9 months ago by ATpoint41k
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1703 users visited in the last hour