I have 10 normal-tumor matched samples of pancreatic cancer. I have generated the vcfs by comparing the tumor-normal samples. Now I have annotated the vcfs to know which variants fall inside which gene. I am now comparing the gene names from the annotated vcfs with the driver gene database to find how many driver genes are present in my samples. After finding all such driver genes from my 10 samples, I can do some set operations to find out which are the commonly mutated genes . I know it's a very naive way to go about it and there are tools in place to find these genes. But is my approach correct?
Question: Finding driver genes from a cancer dataset
2.4 years ago by
banerjeeshayantan • 170
banerjeeshayantan • 170 wrote:
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