gene expression database for quary a gene
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6.6 years ago
rob.costa1234 ▴ 310

Is there a gene expression (RNAseq or array) database that can be be queried for expression level of a particular gene in specific cancer?

Thanks

RNA-Seq • 1.7k views
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In addition to HPRD and cBioPortal, there is CCLE as well which is cell line specific

Though cBioPortal has added advantage of being able to visualize effect of mut. vs. WT on the gene which you have queried.

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6.6 years ago
Michael 55k

How about the Human protein Atlas (sample query). If you are looking for a few genes only, the web-interface provides you with the context to interpret the data properly. Data can be downloaded from there as well. In addition, there is an estimate of the protein expression level and information on the prognostic performance of the gene.

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6.6 years ago
GenoMax 146k

cBioPortal and LinkedOmics.

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6.6 years ago
Rahul Sharma ▴ 660

Although that is very tricky to get gene signatures that could match to your query signatures, as many factor influence the expression profiles e.g cell type used, controls, number of replicates and way of generating expression profiles. Here are few on-line resources that I use for my analyses:

http://www.lincsproject.org/LINCS/tools/workflows/query-a-gene-expression-signature-against-the-lincs-11000-data http://www.expression.cs.cmu.edu/index.html

I hope this would be helpful

Best, Rahul

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