gene expression database for quary a gene
3
1
Entering edit mode
6.2 years ago
rob.costa1234 ▴ 310

Is there a gene expression (RNAseq or array) database that can be be queried for expression level of a particular gene in specific cancer?

Thanks

RNA-Seq • 1.6k views
ADD COMMENT
0
Entering edit mode

In addition to HPRD and cBioPortal, there is CCLE as well which is cell line specific

Though cBioPortal has added advantage of being able to visualize effect of mut. vs. WT on the gene which you have queried.

ADD REPLY
1
Entering edit mode
6.2 years ago
Michael 54k

How about the Human protein Atlas (sample query). If you are looking for a few genes only, the web-interface provides you with the context to interpret the data properly. Data can be downloaded from there as well. In addition, there is an estimate of the protein expression level and information on the prognostic performance of the gene.

ADD COMMENT
0
Entering edit mode
6.2 years ago
GenoMax 141k

cBioPortal and LinkedOmics.

ADD COMMENT
0
Entering edit mode
6.2 years ago
Rahul Sharma ▴ 660

Although that is very tricky to get gene signatures that could match to your query signatures, as many factor influence the expression profiles e.g cell type used, controls, number of replicates and way of generating expression profiles. Here are few on-line resources that I use for my analyses:

http://www.lincsproject.org/LINCS/tools/workflows/query-a-gene-expression-signature-against-the-lincs-11000-data http://www.expression.cs.cmu.edu/index.html

I hope this would be helpful

Best, Rahul

ADD COMMENT

Login before adding your answer.

Traffic: 1999 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6