Question: Beta values for hyper- and hypo- methylated probes
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gravatar for rasii
6 months ago by
rasii0
rasii0 wrote:

Hi all,

I am working on some DNA methylation data and I have used RnBeads to analyse it. I just wanted to know what people have used to classify differentially methylated probes/regions that are hypermethylated, hypomethylated and unmethylated?

From the beta values which is between 0 - 1, what range falls under the above mentioned categories? Can i use >0.8 as hypermethy, <0.2 as hypometh, and what would be methylated and unmethylated.

Is there a paper that gives details of this?

Thanks

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