Question: (Closed) CRAM vs BAM
2
gravatar for roccostorace
2.5 years ago by
roccostorace20
roccostorace20 wrote:

Hello I'd like to know info on BAM and CRAM. Precisely:

What are the main differences between BAM to CRAM?

What are advantages and disadvantages of BAM respects with CRAM and viceversa?

Why BAM is preferred respects to CRAM?

cram bam • 4.9k views
ADD COMMENTlink written 2.5 years ago by roccostorace20
2

Come on, googling this gives you plenty of output, even links to previous Biostars threads where Heng Li, the leading developer of the original SAM format, comments on this.

ADD REPLYlink written 2.5 years ago by ATpoint36k

It is a case of tl:ds.

Here are the current latest specs:

http://samtools.github.io/hts-specs/CRAMv3.pdf

http://samtools.github.io/hts-specs/SAMv1.pdf

ADD REPLYlink written 2.5 years ago by h.mon30k

Partly covered here. Actually CRAM is recommended for long term storage. See here.

ADD REPLYlink written 2.5 years ago by Satyajeet Khare1.5k

Hello roccostorace!

Questions similar to yours can already be found at:

We have closed your question to allow us to keep similar content in the same thread.

If you disagree with this please tell us why in a reply below. We'll be happy to talk about it.

Cheers!

ADD REPLYlink written 2.5 years ago by RamRS28k
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