I need to use the PPI data from BioGRID, given by the OFFICIAL_SYMBOL_A and OFFICIAL_SYMBOL_B columns in the source files. In this project's most recent publication, it is reported that "BioGRID interaction annotation is based on Entrez Gene identifiers for genes and proteins."
Beyond the two columns of data cited above, each source file also contains two corresponding columns of aliases for each main interactor, which are described in the documentation as 'lists of common names' for these genes. However, I haven't been able to determine on which platform(s) these aliases are defined, and am wondering whether I should include these aliases in my PPI analyses, or whether using the single interactor names in Entrez format will be sufficient to effectively capture these interactions.
If anyone understands whether it is good practice to include all of these aliases for each interactor (and whether their platform is Entrez and/or other ontologies), or if using the single Entrez name for each interactor will suffice, I appreciate your insights.