kmer distribution curve shifts to right of poisson distribution
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3.6 years ago
deepti1rao ▴ 40

I plotted my kmer histogram generated by jellyfish and tried fitting it to the poisson distribution. What could be the probable reason for a shift to the right?

https://ibb.co/gfB9Pc

kmer poisson distribution • 853 views
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Please provide context. What are you trying to do?

Poisson distributions can take various forms, by the way, and they differ based on the value of Lambda (λ). Both of your curves look Poison-like to me.

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3.6 years ago
h.mon 33k

I guess the black curve is the actual kmer distribution, and the dashed green is the fitted poisson? I will assume yes:

The tails of your kmer distribution do not fit a poisson, and in particular, the peak of erroneous kmers is probably what is skewing the fitted distribution to the left.

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