Question: Plot linkage disequilibrium along chromosome
1
gravatar for Roy
19 months ago by
Roy10
Roy10 wrote:

I wanted to plot the r2 LD values along chromosomes. I have my table produced with PLINK which has r2 values for each pair of SNPs within 1000 kb windows. One way to do it would be to average the r2 values within each window. But I would like to have the points every 20 kb apart along the chromosome, as I would later run some correlation analysis using these points and other estimates like along chromosome gene density, along chromosome global Fst etc.

So my question is can I average the LD r2 at every 20 kb block inside the 1000 kb windows? Is there any other way to get the LD values along chromosome at every 20 kb apart?

Thanks for any comments and suggestions

ADD COMMENTlink modified 18 months ago by Biostar ♦♦ 20 • written 19 months ago by Roy10
1

A similar question was asked recently with an amazing answer: LD-decay in a r2 vs distance(cm) plot

ADD REPLYlink written 19 months ago by Philipp Bayer6.5k

Hi Philipp, Thanks a lot for your answer, but I am not looking for a plot of r2 and distance between the SNPs, but a chromosome position based mapping of r2 values.

ADD REPLYlink written 19 months ago by Roy10
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