Merge microarray datasetes with same platform
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3.5 years ago

Hi all, I need to merge 10 microarray datasets of the same platform. Any hint how to do it? Is there any R package for this? I found about inSilicoDb but I guess it is not in use anymore. 2 of the datasets are this and this.

Thanks

microarray merge dataset • 774 views
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3.5 years ago
russhh 5.6k

I analyse different datasets separately and then run metaanlysis over the estimated mean/sd of log fold changes. There are other approaches, for example, you can column-bind the datasets together and fit a huge model if your limma skills are up to it and the datasets really are from the same platform. There's a tool called mergeMaid that will help if they aren't from the same platform.

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I thought I'd written this as a comment. I don't have time to find appropriate code to beef this up to 'answer' status

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One of the mods must have decided that there was sufficient detail here for this to qualify as an answer. Answers don't need to completely solve the problem. They can have valuable pointers to put a solution together.

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