Super-enhacer identification with ATAC-Seq
0
0
Entering edit mode
3.4 years ago
Venados ▴ 10

Hello Everyone!

Has anyone tried to identify super-enhancers by applying the ROSE algorithm to ATAC-Seq data?

Any thoughts on why this might or might not work.

Thanks a lot in advance for your comments and ideas!

super-enhancer ROSE ATAC-Seq • 1.5k views
ADD COMMENT
0
Entering edit mode

ROSE expects H3K27ac data, not open chromatin signals. Whatever result you'll get is not what the tool has been designed for.

ADD REPLY
0
Entering edit mode

I see, in other words, ATAC-seq data doesn't correlate well with H3K27ac

ADD REPLY

Login before adding your answer.

Traffic: 2152 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6