Hi! I am working with methylation data from the TCGA Database. I chose the file with the mean signal values among each gene... The data presented is beta-values, which range from 0 to 1, where 0 means the gene is not methylated and 1 that the gene is totally methylated, however there are values in between and I am trying to dycotomize my data into methylated/non-methylated... What is the best way to set a threshold to define my two groups?
Thanks in advance!