Question: FoldX interaction energy and stability
gravatar for shyantani.maiti
21 months ago by
shyantani.maiti0 wrote:

Dear Sir/Madam, I have calculated the interaction energy between protein and another protein in a protein-protein complex using foldX. The value obtained is -0.13 and in another case I obtained the value of interaction energy as -8.

Interaction energy as per calculated by foldX ∆∆Gab = ∆Gab- (∆Ga + ∆Gb)

If I want to predict the stability from interaction energy by foldX, which value of interaction energy should I consider as stable. If the interaction energy decreases from -0.13 to -8, can I say that the binding affinity increases? It would be great if you please cite some references where I can use interaction energy to obtain the desired protein stability.

foldx interaction energy • 506 views
ADD COMMENTlink modified 21 months ago • written 21 months ago by shyantani.maiti0
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 771 users visited in the last hour