Question: Is there a way to use CNVkit without a reference from normal samples?
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leandro.bispo.oliveira • 0 wrote:
I am currently trying to find the CNV in some WGS data.
Is there a command to run CNVkit on a .bam data without using a Reference from Normal Samples?
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modified 2.8 years ago
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h.mon ♦ 32k
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2.8 years ago by
leandro.bispo.oliveira • 0
As far as i know, CNV requires reference genome. If you do not have a reference available, you can either build a de novo reference from your reads or find closest species whose reference file is available.
He is not asking about a reference genome, he is asking about reference (normal) samples.