Question: Pathway Analysis and hypergeometric distribution
gravatar for Mozart
20 months ago by
Mozart140 wrote:

Hello there, I am trying to understand the idea behind pathway analysis and how they try to reduce gene redundancy across multiple pathways. I have just some general idea behind gene-length bias (the higher is the gene length the more likely it is differentially expressed) but I don't really get why the hypergeometric distribution is important in this sense and how it can be useful to reduce this bias.

thanks in advance.

rna-seq gene • 514 views
ADD COMMENTlink written 20 months ago by Mozart140
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