Hi. Studing tool of RealginerTargetCreator, I'm faced with a curious problem.
--known / -known Input VCF file with known indels Any number of VCF files representing known SNPs and/or indels. Could be e.g. dbSNP and/or official 1000 Genomes indel calls. SNPs in these files will be ignored unless the --mismatchFraction argument is used.
About this argument, what's 1000 Genomes indel calls? It is made of someone's genome? I don't understand that why I need information of one person's indel record at using this tool.