I have four whole genome sequencing data files which two files are reverse and two files forward, Right? (Attached in the image):
I want to map these files using the bwa software to the reference genome. Should i combine two reverse files together, and also combine two forward files together? If I should combine, which files should I combine (According to the picture)? And what command line should I use for combine?
Or no need to combine? How to map them to the reference genome?