Question: how to convert top/bot, or plus/minus strand to positive/negative strand
gravatar for lilingjoyo
2.7 years ago by
lilingjoyo40 wrote:

I‘m trying to convert top/bot or plus/minus strand of Illumina genotype array to positive strand of reference genome. Because I want to do imputation which requires my genotype is based on positive strand.

Name    SNP ILMN Strand Customer Strand
1:100292476 [A/G]   TOP TOP
1:101064936 [A/G]   TOP TOP
1:103380393 [T/C]   BOT TOP
1:104303716 [T/C]   BOT TOP
1:104864464 [A/G]   TOP BOT
1:106737318 [A/C]   TOP BOT
1:109439680 [A/G]   TOP TOP
1:111119214 [T/C]   BOT BOT
1:114483147 [A/C]   TOP TOP

I used command of GenGen: old.bim new.bim --intype ilmnab --outtype dbsnp --outfile new.bim 
Error: invalid allele designation (0/A/B expected based on --intype of ilmnab): <1  GSA-rs114420996 0   58814   A   G
genome • 1.4k views
ADD COMMENTlink modified 2.7 years ago by WouterDeCoster45k • written 2.7 years ago by lilingjoyo40
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