**10**wrote:

Hi everyone,

I am trying to do an enrichment analysis with R and compare two protein sets. I have used the compareCluster function from the clusterProfiler package. The plot of my results looks like this image (I got it from the clusterProfiler vignette). The color code indicates the p-adjusted values. I would like to know what is the adjustment method used by compareCluster and how are the p-values calculated. I could find examples on how to use this function, but not a detailed explanation on the statistical analysis. Thank you in advance for the help.