Existing Glycomics/Glycan databases with sugar modifications?
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6.6 years ago
Joe 21k

Does anyone know if there is a glycomics database with info on sugar modifications etc of proteins?

I have a few protein/gene names and would just like to get some indication of whether they're known to be glycated and whether the sugars have been identified.

glycomics database sugars • 1.7k views
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3.6 years ago
Joe 21k

Answering my own question (but not in a remotely exhaustive or even particularly thorough manner 😅):

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As a reference for future search - a list from BiOkeanos - https://biokeanos.com/search?q=glycosylation+glycan&sortName=match&sortOrder=asc (adds to the ones you found).

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3.6 years ago

I believe there are not many large-scale studies on Glycosylation.

Uniprot contains information on Glycosylation, although I think this is based mostly on computational prediction. See this page for more info: https://www.uniprot.org/help/carbohyd

KEGG has the GLYCAN database for glycan structures: https://www.genome.jp/kegg/glycan/ . I think the FTP data contains some annotation between genes and glycans, but I can't access it right now.

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It's certainly a chronically understudied and poorly understood topic. Hopefully this thread will be full of ideas in a few more years ;)

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