I was trying to query a maf file based on variants when I came across two columns: tumor_seq_allele_1 and tumor_seq_allele_2. Now I found out that these two columns are not identical. Also, I know that alleles are different version of the same gene. So what can I say about the variant?
So what can I say about the variant in both cases? That the first case, there are C>T transitions and in the second, G>A transition?