Question: Enhancers associated to miRNA genes
1
gravatar for Jaime Castro-Mondragon
4 months ago by
Oslo
Jaime Castro-Mondragon10 wrote:

Hi

Do you know resources linking human enhancers to promoters of miRNA genes ?

There are many resources providing Enhancer-Promoter associations (FANTOM5, FOCS, JEME), however most of the promoters correspond to protein coding genes.

Around 50% of miRNAs are intragenic, and one possiblity could be take the enhancer associated to the host gene, however the intragenic miRNAs are not necessarily transcribed by the same TSS, or in the same condition or cell type.

Any help is welcome!

Jaime

mirna promoters enhancers • 170 views
ADD COMMENTlink written 4 months ago by Jaime Castro-Mondragon10

Check this: Super-Enhancer-Mediated RNA Processing Revealed by Integrative MicroRNA Network Analysis

ADD REPLYlink written 4 months ago by venu5.6k

Yes, that's a good reference and very nice work (although it cover ~200 out of ~1000 miRNAs in miRBase).

I will use it.

ADD REPLYlink written 4 months ago by Jaime Castro-Mondragon10
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