Reduce reference alternative to same position
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0
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5.9 years ago
roalva1 ▴ 90

Hello,

I have this four lines in a VFC:

9 4118205 CCGA CCGG
9 4118206 CGA CGG
9 4118207 GA GG
9 4118208 A G

At the end, all they are

9 4118208 A G

would you know if there is some tool (i.e. in bcftools) to reduce this?

Thank you very much

vcf • 669 views
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Entering edit mode
5.9 years ago

https://samtools.github.io/bcftools/bcftools.html

beftools norm

Left-align and normalize indels, check if REF alleles match the reference, split multiallelic sites into multiple rows; recover multiallelics from multiple rows.

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I saw this tool, but I thought it just does left align. Thanks!!

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