i would like to search and download the latest possible human reference genome assembly hg38/GRCh38, in order to use it both in the process of sequence alignment of raw reads, as also for variant calling concerning exome sequencing. However, I'm a bit confused about the available options and the different sources, such as UCSC and NCBI. In detail:
1) If i want to download the latest reference genome human assembly available, then this would be the option : ftp://ftp.ncbi.nlm.nih.gov/genomes/all/GCF/000/001/405/GCF_000001405.38_GRCh38.p12 ?
and specifically the option GRCh38.p12_genomic.fna.gz ?
2) Moreover, the alternative option which is "relatively equivalent" from UCSC, is in the following link:
However, this contains the original hg38 assembly of 2013 ? and not the latest release like NCBI from above ? or it also includes the relative updates ?
Thank you in advance,