Question: Gene expression meta analysis
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gravatar for druggable
2.6 years ago by
druggable30
druggable30 wrote:

Hi,

I am analyzing independent RNA-Seq datasets and doing a meta analysis. Is it valid to compare global transcription profiles from multiple datasets based on the fold changes? For each RNA-Seq dataset, I normalize counts within each dataset and then calculate the fold changes of all genes relative to the control. Now, I aim to create a heatmap of all the datasets based on the fold changes.

Thank you very much.

ADD COMMENTlink modified 2.6 years ago • written 2.6 years ago by druggable30

see this related question

ADD REPLYlink modified 2.6 years ago • written 2.6 years ago by egeulgen1.1k
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