Entering edit mode
5.8 years ago
f.a.galkin
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40
I want to use both 16S and WGS metagenomes produced from the same environment in my study. I wonder if I can do the binning for both data sets in the same program and get relatively similar results?
I figure, any closed-reference approach should be acceptable as long as my reference is produced from an extensive genome collection. Perhaps, k-mer based methods are an overkill for 16S, but they still should work well, right?
What program would you use if you had to use it for both 16S and WGS metagenome binning?
I am not sure about 16S binning, but there are some tools for doing integrative analysis of 16S and shotgun sequenced metagenome data like,
Metastats (Paper), FANTOM (Paper)