I have a list of enriched peaks called from rigorous prepared ChIP-seq reads obtained by certain treatment which can activate specific transcription factor. The headers are: 1. RegionID 2. chr 3. start 4. end 5. -log10 q-value (QuEST) 6. -log10 p-value (QuEST) 7. Rank 8. ChIP reads 9. High confidence peaks
My question is:
- Can we interpret the "Rank" for genomic regions in the list as their affinity to the interest TF across genome.
- If yes for question 1, are there any widely accepted models describing the binding order for the interest TF when its concentration or activity gradually increases.
Thanks in advance!