We sequence trios at our lab, and we would like to check if any of the variants lie within protein-protein interaction sites. I found this database called PiSite, a database for protein-protein interaction sites.
For such sites, I can get the AA residues position within a protein, in addition to the protein PDB ID.
With this information in hand, how is it possible to get the genomic position of those specific AA residues ? anyone aware of programming libraries that can help in this case?
The solution I came up with is to download multiple databases and translate coordinates from one database to the other.