Responsibilities
Provide bioinformatics support including project initiation, experimental design, data storage and analysis of high throughput sequencing data from single cell technologies.
Design, develop and maintain analysis software pipelines, as well as custom scripts to perform single-cell genetic, epi-genetic and transcriptional data analysis to determine cell heterogeneity, clonal evolution, immune signatures, and pathways underlying variation in therapeutic effectiveness.
Qualifications and experience
Experience in sequence analysis such as RNA-seq, Exome-seq, Chip-seq and TCR repertories analysis, construction of data processing pipelines, and quality control/quality assurance analysis.
Hands-on experience with open-source bioinformatics and NGS data analysis tools is required.
Proficiency in one or more programming languages such as Python, R, C++, PERL.
About the lab
Based in the NIH Clinical Center; the marrow failure lab of NHLBI/NIH is one of the largest in the world and offers unparalleled direct experience with patients suffering from blood diseases. Clinical and laboratory work are closely connected, and there are multiple opportunities for team research. Work has been published in the New England Journal of Medicine and other general medical journals and in Blood, Haematologica, and Journal of Immunology.
How to apply
Interested individuals should send a cover letter, curriculum vitae and bibliography, and the names and addresses of three references to shouguo.gao@nih.gov
