in Regier et al.: "Functional equivalence of genome sequencing analysis pipelines enables harmonized variant calling across human genetics projects", bioRxiv, doi 10.1101/269316 The use bwa mem in their alignments with the option '-K 100000000'. Also in https://github.com/CCDG/Pipeline-Standardization/blob/master/PipelineStandard.md it is noted: '-K 100000000 to achieve deterministic alignment results (Note: this is a hidden option)'. I could not find any more detailed description of this option. Does anyone know what it does and where this is documented? Thanks a lot!