Techniques for finding tumor purity from Oncomine panel?
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3.0 years ago

Has anyone found success in determining tumor purity from oncomine data? I've run the gambit of purity and heterogeneity tools and all seemed to be geared for WGS or WES, rather than targeted data. This includes Pyclone, PhyloWGS, EXPANDS, and ABSOLUTE.

Any other tools or techniques out there? I understand targeted panels don't offer nearly as much coverage as something like whole exome sequencing, but there still seems to be potential in the more limited number of SNPs and CNVs available.

oncomine oncology purity heterogeneity • 739 views
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