Hey. I want to write a program that uses gpu-blast to make psi-blast several runs and give me the profile as output. Can you help me understand what's psi-blast algoritm do? I found some data about but have problem to understand it well.
please send me some articles or links about this or write me how this works
- I give fasta sequence as query
- blast build profile from alignment
- blast uses profile to search similarity in db (i dont know how it works for now)
- if theres another iteration blast uses alignment from lasst query as new query?
- build a profile from adding to last profile the new alignment new profile?