I want to remove heterozygous genotype data in multi-samples VCF. At first I used bcftools filter -e option, but it made output VCF that lots of sites are deleted because of few heterozygous genotypes. I think this result is not suitable to search valid SNPs. Therefore, I want to convert heterozygous genotype data to missing data for filteration using vcftools later. Could you recommend effective tools?
Question: How can I convert heterozygous genotype data to missing data?
20 months ago by
recycled8345 • 0
recycled8345 • 0 wrote:
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