Hi, does anyone know what is the lowest setup for running hicBuildmarix? I am currently trying to analyze some of the data published by other groups in 4DN portal. I found hicBuildmatrix is quite memory demanding and will gradually eat up all internal memories. typically, I want to build matrix from two .bam file created by bwa mem, which each takes ~10 GB space.I then run hicBuildMatrix with bin set to 10000 (for human genome it's ~300 kb resolution). I found I gradually run out of memory and failed eventually. So, could anyone give some suggestions. I currently don't have access to HPC. Thanks a lot!