Question: mutation vs snp
0
gravatar for fatimarasool135
24 months ago by
fatimarasool13560 wrote:

Hi. I have found the snps by samtools. I want to know the biological significance or annotation of these snps.? how can i found these snps are involved in any disease ?

rna-seq snp • 463 views
ADD COMMENTlink modified 24 months ago by finswimmer13k • written 24 months ago by fatimarasool13560
1
gravatar for h.mon
24 months ago by
h.mon31k
Brazil
h.mon31k wrote:

Use VEP, Annovar, snpEff, ...

You should provide more details, like which organism (human?), did you perform mapping or de novo assembly, which filters did you apply, and so on.

ADD COMMENTlink written 24 months ago by h.mon31k

Mapping with reference genome

ADD REPLYlink written 24 months ago by fatimarasool13560
0
gravatar for finswimmer
24 months ago by
finswimmer13k
Germany
finswimmer13k wrote:

This is a very general question. More details about your aim would be helpful.

This is why I gave you a more general answer: Use VEP from ensembl. If you have an (rs)ID you can also search directly for it on ensembl. For each variant you can find a "phenotype data" page if data are available, e.g. rs699.

fin swimmer

ADD COMMENTlink written 24 months ago by finswimmer13k

i have excel file...in which i have only chromosome number,position of snp ,etc...this excel file not contain any id or genes in which thess snps are known. i want to know the corresponding genes and proteins of snps

ADD REPLYlink written 24 months ago by fatimarasool13560

Than VEP is really the place you should go.

ADD REPLYlink written 24 months ago by finswimmer13k
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 2002 users visited in the last hour