I would like to know the biological significance of common genes of both mRNA and methylation.
For example, of breast cancer data, out of gene-gene network created using methylation features, one can select top '100' genes, similarly, from mRNA gene-gene network if we had selected top '100' genes. Let, the common gene symbols of both mRNA and methylation is 10.
What is these 10 gene symbols biological significance? How to verify their significance?
Thanks & Regards, Reddy Rani V.