Question: Download of FF-FFPE pair DNA seq data
0
gravatar for dkalfakakou
2.2 years ago by
dkalfakakou10
dkalfakakou10 wrote:

Hello everybody!

I was wondering if someone knew where I could find some data from Fresh Frozen/FFPE pairs DNA seq. Are there any public resources?

Thank you!

sequencing genome • 519 views
ADD COMMENTlink modified 2.2 years ago by Kevin Blighe69k • written 2.2 years ago by dkalfakakou10
1
gravatar for Kevin Blighe
2.2 years ago by
Kevin Blighe69k
Republic of Ireland
Kevin Blighe69k wrote:

I found this, after a quick search: Performance comparison of three DNA extraction kits on human whole-exome data from formalin-fixed paraffin-embedded normal and tumor samples (data available at EGA, but may require pre-approval by study author).

You should also note this important study, but I don't know if data is available: Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project. They may have links to other studies, though.

I also found this, but it's RNA-seq: - A Comparison of RNA-Seq Results from Paired Formalin-Fixed Paraffin-Embedded and Fresh-Frozen Glioblastoma Tissue Samples ( data available from NCBI BioPoroject )

ADD COMMENTlink modified 2.2 years ago • written 2.2 years ago by Kevin Blighe69k
1

Thank you very much for taking the time to search and answer! I had already searched for data at BioProject and I couldn't find what I was looking for. I have to admit that I wasn't aware of EGA. I will try to contact the study author. I have already contacted the authors of the 1000G study, but I hadn't had a response. Maybe I will try again.

Thank you once more!

ADD REPLYlink modified 2.2 years ago • written 2.2 years ago by dkalfakakou10
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